In the Byzantine Empire during the sixth century, one of the first recorded instances of what many historians have generally identified as the bubonic plague (or more specifically Justinian’s Plague) brought devastation to the Eastern Roman Empire of the late antiquity period in more ways than one. The immediate effects of the plague were seen and felt by almost everyone alive at the time. At the height of virulence, everyone in and around the empire had seen at least half of their friends and loved ones succumb to the pandemic. Due to shortage of land to bury the dead, streets were littered with stacks of dead, rotting corpses.

plague at ashdod

Plague at Ashdod

Following this first pandemic, survivors – Justinian included – made efforts to rebuild and restructure their empire and its economy but due to the latent effects of the plague, the empire would never fully recover or return to the level of prosperity it once enjoyed. In keeping with points made by Oldstone about viruses and their long-lasting effects on major events and decisions in history and economy, I think it is exemplary of the basic viral-to-host transaction that the bubonic plague, generally believed to have reached Byzantium due to the far-reaching nature of its then thriving economy (trade with neighboring areas, etc), ultimately weakened the same economy that allowed it to spread so quickly in the first place. Should all past, present and future major outbreaks of viruses/plagues be viewed, not as an anomalies, but as inevitable – part and parcel of human advancement much in the same way immunization is devised to combat them?

Biological or (more important and pertinent) computational, is the virus solely responsible for successfully infecting and altering a host cell or should the environment that allows it to spread rapidly be credited for however high a level of virulence the virus is able to achieve? In the specific case of memes in meme culture, how much credit should be given to a video that goes viral for having the right qualities/ingredients to make it go viral? and how much credit should be given to the platform on top of which the video was able to spread so quickly? Does the nature of that platform change over time to reflect the long-lasting effects of highly successful memes on pop and internet culture?

Successful memes go viral, less successful memes don’t. What is the deciding factor for judging a meme as successful or as an isolated incident? Is it quantitative? Is it based on how the meme originated (from an outside agent or as part of the internet turning on itself)? Should a distinction be made between memes that spring up “naturally” (genuinely born on the web… eg: “double rainbow”) and memes that are “manufactured” (perhaps as part of a carefully constructed marketing campaign with deliberate “going viral” potential… eg: “old spice guy”)?

Top 10 Worst Plagues in History

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